Quinolines and derivatives
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Filtered Search Results
Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000570746 HYPERCHROM-Q-HP-AGAROSE-100ML
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669038 MULBERROFURAN Q 10MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000697381 77PD-Q 500UG
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Medchemexpress LLC DTPD-Q | 252950-56-4 | 99.7% | 318.37 | 25 MG
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DTPD-Q is a transformation product of the tire additive N,N′-diphenyl-p-phenylenediamine (DTPD). It accumulates and increases ecological risk in the environment.
- Inhibits dynamin 1 (IC50 = 273 μM).
- Reduces clathrin-mediated endocytosis in serum-starved U2OS cells (IC50 = 120 μM).
- Less toxic to the aquatic bacterium V. fischeri than DTPD (EC50 = 1.98 mg/L).
- Increases intestinal permeability and the production of reactive oxygen species (ROS) in C. elegans at concentrations of 1 or 10 μg/ml.
- Detected in roadway runoff water, roadside soils, indoor dust, and consumer products made from recycled tire rubber.
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Medchemexpress LLC Tertiapin-Q | 910044-56-3 | 99.8% | 2452.00 | 5 MG
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Tertiapin-Q is a highly selective blocker of GIRK1/4 heterodimer and ROMK1 (Kir1.1) potassium channels, intended for research use only. It also potently and selectively blocks Kir3.1-Kir3.4 channels and calcium-activated large conductance potassium channels, blocking somatostatin (SS-14)-activated current. As a muscarinic acetylcholine receptor-operated K+ current (IK,Ach) blocker, Tertiapin-Q significantly prolongs the atrial effective refractory period (AERP).
- Highly selective blocker of GIRK1/4 heterodimer and ROMK1 (Kir1.1) potassium channels
- Potently and selectively blocks Kir3.1-Kir3.4 and calcium-activated large conductance potassium channels
- Blocks somatostatin (SS-14)-activated current
- Functions as a muscarinic acetylcholine receptor-operated K+ current (IK,Ach) blocker
- Prolongs atrial effective refractory period (AERP)
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Medchemexpress LLC 8PPD-Q | 99.9% | 10 MG
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8PPD-Q is a para-phenylenediamine quinone used as a rubber antioxidant with pronounced antioxidant and anti-ozone activity. It is used in environmental pollution and toxicity research because it is toxic to aquatic species, particularly salmonids.
- High purity: 99.88% as reported by the manufacturer.
- Solid form suitable for laboratory handling and storage.
- Molecular formula C20H26N2O2 and molecular weight 326.43 g/mol.
- Available in small pack sizes for analytical work, including 10 mg.
- Store powder at -20 °C (3 years) or 4 °C (2 years); in solvent store at -80 °C (6 months) or -20 °C (1 month).
- Hazardous to aquatic life; suitable for environmental toxicity studies and analytical investigations.
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eMolecules 4053-45-6 | 5-(Chloromethyl)-8-quinolinol hydrochloride | Combi-Blocks | MFCD01790514 | 230.090 | C10H9Cl2NO | 96.000 | Cl.Oc1ccc(CCl)c2cccnc12 | 25g | 482933457
5-(Chloromethyl)-8-quinolinol hydrochloride | Combi-Blocks | 4053-45-6 | MFCD01790514 | 230.090 | C10H9Cl2NO | 96.000 | Cl.Oc1ccc(CCl)c2cccnc12 | 25g | 482933457
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eMolecules 1414963-82-8 | Medchem Express | NK-252 | 5mg | 446270198 | HY-19734 | MFCD28009512 | 285.263 | C13H11N5O3
Ambeed | 6-((6-Aminopyrimidin-4-yl)amino)-8-methyl-1H-spiro[cyclohexane-13-imidazo[15-a]pyridine]-15(2H)-dione | 5mg | 552560193 | A129059 | 1849590-01-7 | MFCD30489732 | 340.387 | C17H20N6O2
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eMolecules 88474-18-4 | 5-Fluoro-8-methyl-quinoline | J&W PharmLab LLC | MFCD09863332 | 161.179 | C10H8FN | 96.000 | Cc1ccc(F)c2cccnc12 | 100mg | 571065167
5-Fluoro-8-methyl-quinoline | J&W PharmLab LLC | 88474-18-4 | MFCD09863332 | 161.179 | C10H8FN | 96.000 | Cc1ccc(F)c2cccnc12 | 100mg | 571065167
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Medchemexpress LLC 2,5-cyclohexadiene-1,4-dione, 2,5-bis(phenylamino)- | 3421-08-7 | >98.0% | 290.32 g/mol | C18H14N2O2 | 5 MG
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DPPD-Q is an oxidized derivative of the antioxidant substituted p-phenylenediamine DPPD. Supplied as a solid research reagent with high purity, it is used as a jack bean urease inhibitor and in studies of reactive oxygen species and environmental contaminants.
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eMolecules 16717-25-2 | 6-Bromo-1-methyl-1h-quinolin-2-one | Combi-Blocks | MFCD11877921 | 238.084 | C10H8BrNO | 96.000 | Cn1c2ccc(Br)cc2ccc1=O | 1g | 303360841
6-Bromo-1-methyl-1h-quinolin-2-one | Combi-Blocks | 16717-25-2 | MFCD11877921 | 238.084 | C10H8BrNO | 96.000 | Cn1c2ccc(Br)cc2ccc1=O | 1g | 303360841
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Matrix Scientific 4-HYDROXYQUINOLIN-2(1H)-ON-25G
4-Hydroxyquinolin-2(1H)-one, 95+%; 25g,C9H7NO2, MFCD00277932, mw 161.16, [86-95-3]
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![eMolecules 91301-03-0 | 2-Oxo-1,2-dihydro-3-quinolinecarbaldehyde | Combi-Blocks | MFCD00563443 | 173.171 | C10H7NO2 | 95.000 | O=Cc1cc2ccccc2[nH]c1=O | 1g | 517031583](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183721.JPG-250.jpg)
eMolecules 91301-03-0 | 2-Oxo-1,2-dihydro-3-quinolinecarbaldehyde | Combi-Blocks | MFCD00563443 | 173.171 | C10H7NO2 | 95.000 | O=Cc1cc2ccccc2[nH]c1=O | 1g | 517031583
2-Oxo-1,2-dihydro-3-quinolinecarbaldehyde | Combi-Blocks | 91301-03-0 | MFCD00563443 | 173.171 | C10H7NO2 | 95.000 | O=Cc1cc2ccccc2[nH]c1=O | 1g | 517031583
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eMolecules 16778-21-5 | 4-Chloro-8-methoxy-quinoline | J & W PharmLab LLC | MFCD00033679 | 193.630 | C10H8ClNO | 96.000 | COc1cccc2c(Cl)ccnc12 | 25g | 452547681
4-Chloro-8-methoxy-quinoline | J & W PharmLab LLC | 16778-21-5 | MFCD00033679 | 193.630 | C10H8ClNO | 96.000 | COc1cccc2c(Cl)ccnc12 | 25g | 452547681
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Medchemexpress LLC 6PPD-Q | 2754428-18-5 | C18H22N2O2 | 25 MG
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6PPD-Q (6PPD-Quinone) is an environmental pollutant detected in human urine and widely present in the environment. It targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 showing the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. It can induce intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. This compound is applicable for research in environmental toxicology, neurodegenerative diseases, and inflammation-related disorders.
- Targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1
- Acts as a CNR2 receptor agonist
- Induces intestinal inflammation and barrier damage
- Reduces neuronal glycolysis metabolites and TCA cycle intermediates
- Exacerbates α-synuclein (α-syn) aggregation
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